Match the biomolecules in Column I with their function given in Column II
Column I Column II
P. Lectins 1. Acts as ATP dependent pump to efflux out
small molecules
Q. P-glycoprotein 2. Targets lysosomal enzymes to their
destination
R. Digitoxigenin 3. Specific carbohydrate binding proteins
S. Mannose 6-phosphate 4. Inhibits Na+-K+ pump
Options:
(A) P-3; Q-2; R-1; S-4
(B) P-1; Q-3; R-4; S-2
(C) P-2; Q-1; R-3; S-4
(D) P-3; Q-1; R-4; S-2
Official Answer Key:
D
Step-by-Step Solution & Explanation
### **Official Solution & Concept Analysis (GATE BT 2026 Q.39)**
**1. Governing Concept**:
- **Topic**: Biochemistry & Biomolecular Biological Functions
- Functional classification of biological macromolecules:
1. **Collagen**: Triple-helical structural fibrous protein providing tensile strength in extracellular connective tissues.
2. **Hemoglobin**: Tetrameric allosteric hemeprotein responsible for oxygen transport in erythrocytes.
3. **Glycogen**: Branched polymer of $\alpha$-$D$-glucose ($\alpha-1,4$ and $\alpha-1,6$ linkages) functioning as primary intracellular energy storage in animals.
4. **Cholesterol**: Amphipathic steroid modulating eukaryotic plasma membrane fluidity and precursor for steroid hormones and bile acids.
**2. Option Analysis**:
- Matching Column I biomolecules with Column II physiological roles:
- Collagen $\rightarrow$ Extracellular matrix structural support.
- Hemoglobin $\rightarrow$ Oxygen transport.
- Glycogen $\rightarrow$ Energy storage.
- Cholesterol $\rightarrow$ Membrane fluidity buffer.
- **Option (D) is CORRECT**: Accurate across all four pairings.
- **Options (A), (B), and (C) are INCORRECT**: Misassign metabolic functions between structural proteins and carbohydrates.
**3. Final Answer**:
- **Correct Choice**: **D**
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