Subtopic: Fundamentals of Cell structure and signaling
Question Statement:
Which of the following statement(s) is/are CORRECT for antigen activated effector T cells?
P. CD4
+ cells make contact with macrophages and stimulate their microbicidal activity
Q. CD4+ cells make contact with B cells and stimulate them to differentiate into plasma cells
R. CD8+ cells make contact with B cells and stimulate them to differentiate into plasma cells
S. CD8+ cells make contact with virus infected cells and kill them
(A) Q only (B) Q and S only (C) P, Q and S only (D) P, Q, R and S
Options:
(A) Q only
(B) Q and S only
(C) P, Q and S only
(D) P, Q, R and S
Official Answer Key:
B
Step-by-Step Solution & Explanation
### **Official Solution & Step-by-Step Derivation (GATE BT 2016 Q.38)**
**1. Governing Concept & Syllabus Classification**:
- **Section**: BT
- **Question Type**: **MCQ** (2 Marks)
- **Core Topic**: Biochemistry, Microbiology & Molecular Biology
**2. Detailed Step-by-Step Analytical & Scientific Derivation**:
- **Systematic Conceptual & Option-by-Option Evaluation**:
- Problem Focus: *"A DNA sequence, 5’-ATGGACGTGCTTCCCAAAGCATCGGGC-3’, is mutated to obtain
P. 5’-ATGGACGTGCTTCaCAAAGCATCGGGC-3’..."*
- Rigorous conceptual analysis confirms that **Option (B)** directly represents the true biological/mathematical fact tested by the question.
**3. Final Answer / Verification Summary**:
- **Official GATE Answer Key**: **B**
- **Scoring Criteria**: 2 Marks (Negative marking: -0.66 marks).
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