GATE BT 2015 • Q24
MCQ • 1 Mark
Section 2: General Biotechnology
Biomolecules, enzyme kinetics
Subtopic: Fundamentals of Biomolecules, enzyme kinetics
Question Statement:
Production of monoclonal antibodies by hybridoma technology requires
Options:
-
(A) splenocytes
-
(B) osteocytes
-
(C) hepatocytes
-
(D) thymocytes
Step-by-Step Solution & Explanation
### **Official Solution & Step-by-Step Derivation (GATE BT 2015 Q.24)**
**1. Governing Concept & Syllabus Classification**:
- **Section**: BT
- **Question Type**: **MCQ** (1 Mark)
- **Core Topic**: Biochemistry, Microbiology & Molecular Biology
**2. Detailed Step-by-Step Analytical & Scientific Derivation**:
- **Systematic Conceptual & Option-by-Option Evaluation**:
- Problem Focus: *"Production of monoclonal antibodies by hybridoma technology requires..."*
- **Option (A) [CORRECT]**: *"splenocytes"*
- Validated by canonical biochemistry/biotechnology literature. Specifically matches the molecular mechanism, kinetic model, or empirical finding required.
- **Option (B) [INCORRECT]**: *"osteocytes"* does not satisfy the precise boundary conditions or molecular specificity.
- **Option (C) [INCORRECT]**: *"hepatocytes"* does not satisfy the precise boundary conditions or molecular specificity.
- **Option (D) [INCORRECT]**: *"thymocytes
Options :
1. V A
2. * B
3. * C
4. *D"* does not satisfy the precise boundary conditions or molecular specificity.
**3. Final Answer / Verification Summary**:
- **Official GATE Answer Key**: **A**
- **Scoring Criteria**: 1 Mark (Negative marking: -0.33 marks).
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