GATE BT 2015 • Q11
MCQ • 1 Mark
Section 4: Bioprocess Engineering and Process Biotechnology
Downstream processing (chromatography, filtration)
Subtopic: Fundamentals of Downstream processing (chromatography, filtration)
Question Statement:
Which one of the following complement proteins is the initiator of the membrane attack complex?
(А) СЗа
(В) СЗЪ
Step-by-Step Solution & Explanation
### **Official Solution & Step-by-Step Derivation (GATE BT 2015 Q.11)**
**1. Governing Concept & Syllabus Classification**:
- **Section**: BT
- **Question Type**: **MCQ** (1 Mark)
- **Core Topic**: Biochemistry, Microbiology & Molecular Biology
**2. Detailed Step-by-Step Analytical & Scientific Derivation**:
- **Systematic Conceptual & Option-by-Option Evaluation**:
- Problem Focus: *"Which one of the following complement proteins is the initiator of the membrane attack complex?
(А) СЗа
(В) СЗЪ..."*
- **Option (D) [CORRECT]**: *"C5b
Options :
1. *
2.
*B
3. * C
4.0 D"*
- Validated by canonical biochemistry/biotechnology literature. Specifically matches the molecular mechanism, kinetic model, or empirical finding required.
- **Option (C) [INCORRECT]**: *"CSa"* does not satisfy the precise boundary conditions or molecular specificity.
**3. Final Answer / Verification Summary**:
- **Official GATE Answer Key**: **D**
- **Scoring Criteria**: 1 Mark (Negative marking: -0.33 marks).
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