Subtopic: Fundamentals of Biomolecules, enzyme kinetics
Question Statement:
In a relatively large but finite and closed population of sexually reproducing diploid organisms, the
frequency of homozygous genotype PP changes from 0.40 to 0.50 and that of pp changes from 0.40
to 0.41 in a span of 10 generations. Which of the following is the most likely cause for the above
change in frequency of the PP genotype?
(A) Non-random mating (B) Random genetic drift
(C) Selection (D) Combination of non-random mating and random genetic drift
Options:
(A) Non-random mating
(B) Random genetic drift
(C) Selection
(D) Combination of non-random mating and random genetic drift
Official Answer Key:
C
Step-by-Step Solution & Explanation
### **Official Solution & Step-by-Step Derivation (GATE BT 2014 Q.35)**
**1. Governing Concept & Syllabus Classification**:
- **Section**: BT
- **Question Type**: **MCQ** (1 Mark)
- **Core Topic**: Biochemistry, Microbiology & Molecular Biology
**2. Detailed Step-by-Step Analytical & Scientific Derivation**:
- **Systematic Conceptual & Option-by-Option Evaluation**:
- Problem Focus: *"The growth medium for mammalian cells contains serum. One of the major functions of serum is to
stimulate cell growth and attachment. However, it must be filter sterilized to..."*
- **Option (C) [CORRECT]**: *"remove mycoplasma and microorganisms"*
- Validated by canonical biochemistry/biotechnology literature. Specifically matches the molecular mechanism, kinetic model, or empirical finding required.
- **Option (A) [INCORRECT]**: *"remove large proteins"* does not satisfy the precise boundary conditions or molecular specificity.
- **Option (B) [INCORRECT]**: *"remove collagen only"* does not satisfy the precise boundary conditions or molecular specificity.
- **Option (D) [INCORRECT]**: *"remove foaming agents
BT
3/9
BT (GATE 2014)
GATE 2014 "* does not satisfy the precise boundary conditions or molecular specificity.
**3. Final Answer / Verification Summary**:
- **Official GATE Answer Key**: **C**
- **Scoring Criteria**: 1 Mark (Negative marking: -0.33 marks).
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