GATE BT 2013 • Q6 MCQ • 1 Mark

Section 2: General Biotechnology

Cell structure and signaling

Subtopic: Fundamentals of Cell structure and signaling

Question Statement:

In vaccine formulations and immunological assays, the role of an adjuvant is to:

Options:

  • (A) prolong the persistence of antigen and enhance immune response
  • (B) cross link the antigen to eliminate immunogenicity
  • (C) increase the rate of antigen degradation
  • (D) neutralize circulating protective antibodies

Official Answer Key:

A

Step-by-Step Solution & Explanation

### **Official Solution & Step-by-Step Derivation (GATE BT 2013 Q.6)** **1. Governing Concept & Syllabus Classification**: - **Section**: BT - **Question Type**: **MCQ** (1 Mark) - **Core Topic**: Quantitative & Analytical Aptitude **2. Detailed Step-by-Step Analytical & Scientific Derivation**: - **Systematic Conceptual & Option-by-Option Evaluation**: - Problem Focus: *"In vaccine formulations and immunological assays, the role of an adjuvant is to:..."* - **Option (A) [CORRECT]**: *"prolong the persistence of antigen and enhance immune response"* - Validated by canonical biochemistry/biotechnology literature. Specifically matches the molecular mechanism, kinetic model, or empirical finding required. - **Option (B) [INCORRECT]**: *"cross link the antigen to eliminate immunogenicity"* does not satisfy the precise boundary conditions or molecular specificity. - **Option (C) [INCORRECT]**: *"increase the rate of antigen degradation"* does not satisfy the precise boundary conditions or molecular specificity. - **Option (D) [INCORRECT]**: *"neutralize circulating protective antibodies"* does not satisfy the precise boundary conditions or molecular specificity. **3. Final Answer / Verification Summary**: - **Official GATE Answer Key**: **A** - **Scoring Criteria**: 1 Mark (Negative marking: -0.33 marks).

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