Section 3: Genetics, Cellular and Molecular Biology
DNA replication, transcription, translation
Subtopic: Fundamentals of DNA replication, transcription, translation
Question Statement:
Match the antibioticsinGroup Iwith the targets inGroup II.
Group I
Group II
P. Sulfonamide 1. Peptidoglycan synthesis
Q. Quinolones 2. Peptide chain elongation
R. Erythromycin 3. Folic acid biosynthesis
S. Cephalosporin 4. Topoisomerase
(A) P-3, Q-4, R-1, S-2 (B) P-2, Q-4, R-3, S-1
(C) P-4, Q-1, R-2, S-3 (D) P-3, Q-4, R-2, S-1
Options:
(A) P-3, Q-4, R-1, S-2
(B) P-2, Q-4, R-3, S-1
(C) P-4, Q-1, R-2, S-3
(D) P-3, Q-4, R-2, S-1
Official Answer Key:
D
Step-by-Step Solution & Explanation
### **Official Solution & Step-by-Step Derivation (GATE BT 2013 Q.30)**
**1. Governing Concept & Syllabus Classification**:
- **Section**: BT
- **Question Type**: **MCQ** (2 Marks)
- **Core Topic**: Biochemistry, Microbiology & Molecular Biology
**2. Detailed Step-by-Step Analytical & Scientific Derivation**:
- **Systematic Conceptual & Option-by-Option Evaluation**:
- Problem Focus: *"Match the antibioticsinGroup Iwith the targets inGroup II.
Group I
Group II
P. Sulfonamide 1. Peptidoglycan synthesis
Q. Quinolones 2. Peptide chain elongation
R. Erythromycin 3. Folic acid biosynthesis
S. Ceph..."*
- **Option (D) [CORRECT]**: *"P-3, Q-4, R-2, S-1"*
- Validated by canonical biochemistry/biotechnology literature. Specifically matches the molecular mechanism, kinetic model, or empirical finding required.
- **Option (A) [INCORRECT]**: *"P-3, Q-4, R-1, S-2"* does not satisfy the precise boundary conditions or molecular specificity.
- **Option (B) [INCORRECT]**: *"P-2, Q-4, R-3, S-1"* does not satisfy the precise boundary conditions or molecular specificity.
- **Option (C) [INCORRECT]**: *"P-4, Q-1, R-2, S-3"* does not satisfy the precise boundary conditions or molecular specificity.
**3. Final Answer / Verification Summary**:
- **Official GATE Answer Key**: **D**
- **Scoring Criteria**: 2 Marks (Negative marking: -0.66 marks).
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