Section 3: Genetics, Cellular and Molecular Biology
DNA replication, transcription, translation
Subtopic: Fundamentals of DNA replication, transcription, translation
Question Statement:
Match the terms in Group I with their associated functions in Group II.
Group I
Group II
Q. Leucine zipper
P. Shine-Dalgarno sequences
1. Aminoacylation of tRNA
2.
Gene silencing
R. Aminoacyl tRNA synthetase
3.
Ribosome binding and facilitation of
S. RNA interference (RNAi)
translation initiation
4.
Transcription factors
Options:
(A) P-3, Q-4, R-1, S-2
(C) P-2, Q-3, R-1, S-4
(B) P-4, Q-3, R-2, S-1
(D) P-3, Q-2, R-4, S-1
Official Answer Key:
A
Step-by-Step Solution & Explanation
### **Official Solution & Step-by-Step Derivation (GATE BT 2011 Q.39)**
**1. Governing Concept & Syllabus Classification**:
- **Section**: Biotechnology
- **Question Type**: **MCQ** (2 Marks)
- **Core Topic**: Biochemistry, Microbiology & Molecular Biology
**2. Detailed Step-by-Step Analytical & Scientific Derivation**:
- **Systematic Conceptual & Option-by-Option Evaluation**:
- Problem Focus: *"Match the terms in Group I with their associated functions in Group II.
Group I
Group II
Q. Leucine zipper
P. Shine-Dalgarno sequences
1. Aminoacylation of tRNA
2.
Gene silencing
R. Aminoacyl tRNA synthetase
3.
Ribosome ..."*
- **Option (A) [CORRECT]**: *"P-3, Q-4, R-1, S-2"*
- Validated by canonical biochemistry/biotechnology literature. Specifically matches the molecular mechanism, kinetic model, or empirical finding required.
- **Option (C) [INCORRECT]**: *"P-2, Q-3, R-1, S-4"* does not satisfy the precise boundary conditions or molecular specificity.
- **Option (B) [INCORRECT]**: *"P-4, Q-3, R-2, S-1"* does not satisfy the precise boundary conditions or molecular specificity.
- **Option (D) [INCORRECT]**: *"P-3, Q-2, R-4, S-1"* does not satisfy the precise boundary conditions or molecular specificity.
**3. Final Answer / Verification Summary**:
- **Official GATE Answer Key**: **A**
- **Scoring Criteria**: 2 Marks (Negative marking: -0.66 marks).
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