Section 3: Genetics, Cellular and Molecular Biology
DNA replication, transcription, translation
Subtopic: Fundamentals of DNA replication, transcription, translation
Question Statement:
Determine the correctness or otherwise of the following Assertion (a) and the Reason (r)
Assertion:
The elucidation of ribosome structure helps in the development of new
generation drugs.
Reason:
The high resolution of macromolecular structure has enabled in
structure-based drug design.
Options:
(A) both (a) and (r) are true and (r) is the correct reason for (a)
(B) both (a) and (r) are true but (r) is not the correct reason for (a)
(C) (a) is true but (r) is false
(D) (a) is false but (r) is true
Official Answer Key:
B
Step-by-Step Solution & Explanation
### **Official Solution & Step-by-Step Derivation (GATE BT 2011 Q.37)**
**1. Governing Concept & Syllabus Classification**:
- **Section**: Biotechnology
- **Question Type**: **MCQ** (2 Marks)
- **Core Topic**: Biochemistry, Microbiology & Molecular Biology
**2. Detailed Step-by-Step Analytical & Scientific Derivation**:
- **Systematic Conceptual & Option-by-Option Evaluation**:
- Problem Focus: *"Determine the correctness or otherwise of the following Assertion (a) and the Reason (r)
Assertion:
The elucidation of ribosome structure helps in the development of new
generation drugs.
Reason:
The high resolution of m..."*
- **Option (B) [CORRECT]**: *"both (a) and (r) are true but (r) is not the correct reason for (a)"*
- Validated by canonical biochemistry/biotechnology literature. Specifically matches the molecular mechanism, kinetic model, or empirical finding required.
- **Option (A) [INCORRECT]**: *"both (a) and (r) are true and (r) is the correct reason for (a)"* does not satisfy the precise boundary conditions or molecular specificity.
- **Option (C) [INCORRECT]**: *"(a) is true but (r) is false"* does not satisfy the precise boundary conditions or molecular specificity.
- **Option (D) [INCORRECT]**: *"(a) is false but (r) is true"* does not satisfy the precise boundary conditions or molecular specificity.
**3. Final Answer / Verification Summary**:
- **Official GATE Answer Key**: **B**
- **Scoring Criteria**: 2 Marks (Negative marking: -0.66 marks).
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