GATE BT 2011 • Q3
MCQ • 1 Mark
Section 4: Bioprocess Engineering and Process Biotechnology
Downstream processing (chromatography, filtration)
Subtopic: Fundamentals of Downstream processing (chromatography, filtration)
Question Statement:
Apoptosis is a form of programmed cell death characterized by specific morphological and biochemical features including:
Options:
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(A) necrosis
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(B) programmed cell death
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(C) membrane leaky syndrome
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(D) cell cycle arrest process
Step-by-Step Solution & Explanation
### **Official Solution & Step-by-Step Derivation (GATE BT 2011 Q.3)**
**1. Governing Concept & Syllabus Classification**:
- **Section**: Biotechnology
- **Question Type**: **MCQ** (1 Mark)
- **Core Topic**: Quantitative & Analytical Aptitude
**2. Detailed Step-by-Step Analytical & Scientific Derivation**:
- **Systematic Conceptual & Option-by-Option Evaluation**:
- Problem Focus: *"Apoptosis is a form of programmed cell death characterized by specific morphological and biochemical features including:..."*
- **Option (B) [CORRECT]**: *"programmed cell death"*
- Validated by canonical biochemistry/biotechnology literature. Specifically matches the molecular mechanism, kinetic model, or empirical finding required.
- **Option (A) [INCORRECT]**: *"necrosis"* does not satisfy the precise boundary conditions or molecular specificity.
- **Option (C) [INCORRECT]**: *"membrane leaky syndrome"* does not satisfy the precise boundary conditions or molecular specificity.
- **Option (D) [INCORRECT]**: *"cell cycle arrest process"* does not satisfy the precise boundary conditions or molecular specificity.
**3. Final Answer / Verification Summary**:
- **Official GATE Answer Key**: **B**
- **Scoring Criteria**: 1 Mark (Negative marking: -0.33 marks).
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