Subtopic: Fundamentals of Cell structure and signaling
Question Statement:
Match the viruses in Group I with their host cell receptors in Group II.
Group I
Group I
P. Hepatitis A virus
1. Heparan sulphate
Q. Human immunodeficiency virus
R
Rabies virus
2. Acetylcholine receptor
3. CD4 protein
S. Herpes simplex virus type I
4. Alpha-2 macroglobulin
Options:
(A) P-1, Q-3, R-2, S-
(C) P-4, Q-3, K-2, s-.
(B) P-3, Q-4, R-1, S-
(D) P-2, Q-3, R-1, S-
Official Answer Key:
C
Step-by-Step Solution & Explanation
### **Official Solution & Step-by-Step Derivation (GATE BT 2011 Q.26)**
**1. Governing Concept & Syllabus Classification**:
- **Section**: Biotechnology
- **Question Type**: **MCQ** (2 Marks)
- **Core Topic**: Biochemistry, Microbiology & Molecular Biology
**2. Detailed Step-by-Step Analytical & Scientific Derivation**:
- **Systematic Conceptual & Option-by-Option Evaluation**:
- Problem Focus: *"Match the viruses in Group I with their host cell receptors in Group II.
Group I
Group I
P. Hepatitis A virus
1. Heparan sulphate
Q. Human immunodeficiency virus
R
Rabies virus
2. Acetylcholine receptor
3. CD4 protein
S...."*
- **Option (C) [CORRECT]**: *"P-4, Q-3, K-2, s-."*
- Validated by canonical biochemistry/biotechnology literature. Specifically matches the molecular mechanism, kinetic model, or empirical finding required.
- **Option (A) [INCORRECT]**: *"P-1, Q-3, R-2, S-"* does not satisfy the precise boundary conditions or molecular specificity.
- **Option (B) [INCORRECT]**: *"P-3, Q-4, R-1, S-"* does not satisfy the precise boundary conditions or molecular specificity.
- **Option (D) [INCORRECT]**: *"P-2, Q-3, R-1, S-"* does not satisfy the precise boundary conditions or molecular specificity.
**3. Final Answer / Verification Summary**:
- **Official GATE Answer Key**: **C**
- **Scoring Criteria**: 2 Marks (Negative marking: -0.66 marks).
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