GATE BT 2010 • Q7
MCQ • 1 Mark
Section 3: Genetics, Cellular and Molecular Biology
Recombinant DNA technology
Subtopic: Fundamentals of Recombinant DNA technology
Question Statement:
In transgenics, alterations in the sequence of nucleotide in genes are due to:
P. Substitution
Q. Deletion
R. Insertion
S. Rearrangement
Options:
-
(A) P and Q
-
(B) P, Q and R
-
(C) Q and R
-
(D) R and S
Step-by-Step Solution & Explanation
### **Official Solution & Step-by-Step Derivation (GATE BT 2010 Q.7)**
**1. Governing Concept & Syllabus Classification**:
- **Section**: Biotechnology
- **Question Type**: **MCQ** (1 Mark)
- **Core Topic**: Quantitative & Analytical Aptitude
**2. Detailed Step-by-Step Analytical & Scientific Derivation**:
- **Systematic Conceptual & Option-by-Option Evaluation**:
- Problem Focus: *"In transgenics, alterations in the sequence of nucleotide in genes are due to
P.
Substitution
0.
Deletion
R.
Insertion
Rearrangement..."*
- **Option (B) [CORRECT]**: *"P. Q and R"*
- Validated by canonical biochemistry/biotechnology literature. Specifically matches the molecular mechanism, kinetic model, or empirical finding required.
- **Option (A) [INCORRECT]**: *"Pand Q"* does not satisfy the precise boundary conditions or molecular specificity.
- **Option (C) [INCORRECT]**: *"Q and R"* does not satisfy the precise boundary conditions or molecular specificity.
- **Option (D) [INCORRECT]**: *"R and S"* does not satisfy the precise boundary conditions or molecular specificity.
**3. Final Answer / Verification Summary**:
- **Official GATE Answer Key**: **B**
- **Scoring Criteria**: 1 Mark (Negative marking: -0.33 marks).
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