Subtopic: Fundamentals of Downstream processing (chromatography, filtration)
Question Statement:
Determine the correctness or otherwise of the following Assertion [a] and Reason [r]:
[a] Gram-negative bacteria are more resistant to penicillins than Gram-positive bacteria.
[r] The outer membrane of Gram-negative bacteria acts as a permeability barrier to penicillins.
Options:
(A) Both [a] and [r] are true and [r] is the correct reason for [a]
(B) Both [a] and [r] are true and [r] is not the correct reason for [a]
(C) [a] is true but [r] is false
(D) [a] is false but [r] is true
Official Answer Key:
A
Step-by-Step Solution & Explanation
### **Official Solution & Step-by-Step Derivation (GATE BT 2010 Q.26)**
**1. Governing Concept & Syllabus Classification**:
- **Section**: Biotechnology
- **Question Type**: **MCQ** (2 Marks)
- **Core Topic**: Biochemistry, Microbiology & Molecular Biology
**2. Detailed Step-by-Step Analytical & Scientific Derivation**:
- **Systematic Conceptual & Option-by-Option Evaluation**:
- Problem Focus: *"Decermine the correctness or otherwise of the following Assertion (a) and the Reason (r)
Assertion:
Somatic embryogenesis in plants is a two slep process comprising of embryc
Reason:
Embryo initiation is indepeudent of t..."*
- **Option (C) [CORRECT]**: *"(a) is true but (r) is false
(1))
(a) is false but (r) is true
cortect reason for (a)
BT
--- PAGE 5 ---
2010
BT"*
- Validated by canonical biochemistry/biotechnology literature. Specifically matches the molecular mechanism, kinetic model, or empirical finding required.
- **Option (A) [INCORRECT]**: *"both (a) and (r) are true and (r) is the
cortect reason for (a)
(3)
hoth fa"* does not satisfy the precise boundary conditions or molecular specificity.
**3. Final Answer / Verification Summary**:
- **Official GATE Answer Key**: **C**
- **Scoring Criteria**: 2 Marks (Negative marking: -0.66 marks).
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