GATE BT 2010 • Q2
MCQ • 1 Mark
Section 4: Bioprocess Engineering and Process Biotechnology
Downstream processing (chromatography, filtration)
Subtopic: Fundamentals of Downstream processing (chromatography, filtration)
Question Statement:
Ames test is used to determine
Options:
-
(A) the mutagenicity of a chemical
-
(B) carcinogenicity of a chemical
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(C) both mutagenicity and carcinogenicity of a chemical
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(D) toxicity of a chemical
Step-by-Step Solution & Explanation
### **Official Solution & Step-by-Step Derivation (GATE BT 2010 Q.2)**
**1. Governing Concept & Syllabus Classification**:
- **Section**: Biotechnology
- **Question Type**: **MCQ** (1 Mark)
- **Core Topic**: Quantitative & Analytical Aptitude
**2. Detailed Step-by-Step Analytical & Scientific Derivation**:
- **Systematic Conceptual & Option-by-Option Evaluation**:
- Problem Focus: *"-D Electrophoresis
1. Biochips
S. Microarray
R. Affinity chromatography
2. Syber Green
3. Antibody linked sephrose beads
4. Ampholyles..."*
- **Option (A) [CORRECT]**: *"P-1. Q-2. R4. 5-3"*
- Validated by canonical biochemistry/biotechnology literature. Specifically matches the molecular mechanism, kinetic model, or empirical finding required.
- **Option (B) [INCORRECT]**: *"P-2, Q-4, R-3, S-1"* does not satisfy the precise boundary conditions or molecular specificity.
- **Option (D) [INCORRECT]**: *"P.2. Q-3. R-4. S-1
P.3. Q-2. R-1,5-4
816
--- PAGE 9 ---
2010
BT
Common Dat"* does not satisfy the precise boundary conditions or molecular specificity.
**3. Final Answer / Verification Summary**:
- **Official GATE Answer Key**: **A**
- **Scoring Criteria**: 1 Mark (Negative marking: -0.33 marks).
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