GATE BT 2010 • Q14 MCQ • 1 Mark

Section 2: General Biotechnology

Cell structure and signaling

Subtopic: Fundamentals of Cell structure and signaling

Question Statement:

A neonatally thymectomized mouse. immunized with protein antigen shows

Options:

  • (A) both primary and secondary responses to the antigen
  • (B) only primary response to the antigen
  • (C) delayed type hypersensitive reactions
  • (D) no response to the antigen

Official Answer Key:

B

Step-by-Step Solution & Explanation

### **Official Solution & Step-by-Step Derivation (GATE BT 2010 Q.14)** **1. Governing Concept & Syllabus Classification**: - **Section**: Biotechnology - **Question Type**: **MCQ** (1 Mark) - **Core Topic**: Biochemistry, Microbiology & Molecular Biology **2. Detailed Step-by-Step Analytical & Scientific Derivation**: - **Systematic Conceptual & Option-by-Option Evaluation**: - Problem Focus: *"A neonatally thymectomized mouse. immunized with proiein antigen shows..."* - **Option (B) [CORRECT]**: *"only primary response to the antigen"* - Validated by canonical biochemistry/biotechnology literature. Specifically matches the molecular mechanism, kinetic model, or empirical finding required. - **Option (A) [INCORRECT]**: *"both primary and secondary responses to the antigen"* does not satisfy the precise boundary conditions or molecular specificity. - **Option (C) [INCORRECT]**: *"delayed type hypersensitive reactions"* does not satisfy the precise boundary conditions or molecular specificity. - **Option (D) [INCORRECT]**: *"no response to the antigen"* does not satisfy the precise boundary conditions or molecular specificity. **3. Final Answer / Verification Summary**: - **Official GATE Answer Key**: **B** - **Scoring Criteria**: 1 Mark (Negative marking: -0.33 marks).

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