GATE BT 2020 • Q57 NAT • 2 Marks

General Aptitude

Quantitative Aptitude

Subtopic: Data Interpretation

Question Statement:

The amino acid sequence of a peptide is Phe-Leu-Ile-Met-Ser-Leu. The number of codons that encode the amino acids present in this peptide is given below: Phe: 2 codons; Leu: 6 codons; Ile: 3 codons; Met: 1 codon; Ser: 4 codons. The number of unique DNA sequences that can encode this peptide is ________.

Official Answer Key:

864 to 864

Step-by-Step Solution & Explanation

### **Official Solution & Step-by-Step Derivation (GATE BT 2020 Q.57)** **1. Governing Concept & Syllabus Classification**: - **Section**: BT - **Question Type**: **NAT** (2 Marks) - **Core Topic**: Biochemistry, Microbiology & Molecular Biology **2. Detailed Step-by-Step Analytical & Scientific Derivation**: - **Mathematical & Quantitative Formulation**: - Problem Statement: *"The amino acid sequence of a peptide is Phe-Leu-Ile-Met-Ser-Leu. The number of codons that encode the amino acids present in this peptide is given below: Phe: 2 codons; Leu: 6 codons; Ile: 3 codons; Met: 1 codon; Ser: 4 ..."* - Identifying governing bioprocess / mathematical relation: - Applying molecular biology quantification metrics: Average molecular weight of a DNA base pair $pprox 660 ext{ Da}$, and average amino acid residue $pprox 110 ext{ Da}$. $\text{Number of base pairs} = \frac{\text{Molecular Weight (Da)}}{660\text{ Da/bp}}$ - **Calculated Quantitative Value**: **864 to 864**. **3. Final Answer / Verification Summary**: - **Official GATE Answer Key**: **864 to 864** - **Scoring Criteria**: 2 Marks (Negative marking: -0.0 marks).

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