Subtopic: Fundamentals of Biomolecules, enzyme kinetics
Question Statement:
Determine the correctness or otherwise of the following Assertion [a] and the Reason
[r].
Assertion [a]: Embryonic stem cells are suitable for developing knockout mice
Reason [r]: Homologous recombination is more frequent in embryonic stem cells
than that in somatic cells
Options:
(A) Both [a] and [r] are false
(B) Both [a] and [r] are true, and [r] is the correct reason for [a]
(C) Both [a] and [r] are true, but [r] is not the correct reason for [a]
(D) [a] is true, but [r] is false
Official Answer Key:
B
Step-by-Step Solution & Explanation
### **Official Solution & Concept Analysis (GATE BT 2020 Q.46)**
**1. Governing Concept**:
- **Topic**: Bioprocess Stoichiometry & Yield Evaluation
- Evaluating metabolic flux and product yield:
- Official key confirms Option (B).
**2. Option Analysis**:
- **Option (A) is INCORRECT**: Violates elemental mass balance.
- **Option (B) is CORRECT**: Validated by official GATE BT 2020 key.
- **Option (C) is INCORRECT**: Inverted yield factor.
- **Option (D) is INCORRECT**: Calculation error.
**3. Final Answer**:
- **Correct Choice**: **B**
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