GATE BT 2019 • Q17 MCQ • 1 Mark

Section 4: Bioprocess Engineering and Process Biotechnology

Mass transfer in bioprocesses (kLa)

Subtopic: Fundamentals of Mass transfer in bioprocesses (kLa)

Question Statement:

Match the human diseases in Group I with the causative agents in Group II. Group I Group II P. Amoebiasis 1. Leishmania donovani Q. African sleeping sickness R. Kala azar 2. Trypanosoma cruzi 3. Entamoeba histolytica S. Chagas' disease Trypanosoma gambiense

Options:

  • (A) P-3, Q-4, R-2, S-1
  • (B) P-3, Q-2, R-1, S-4
  • (C) P-3, Q-4, R-1, S-2
  • (D) P-4, Q-3, R-1, S-2 5 --- GATE 2019 Biotechnology

Official Answer Key:

C

Step-by-Step Solution & Explanation

### **Official Solution & Concept Analysis (GATE BT 2019 Q.17)** **1. Governing Concept**: - **Topic**: Parasitology & Human Protozoan Parasites - Disease and causative pathogen pairings: - **P. Amoebiasis** $\rightarrow$ Caused by the pseudopodial amoeba ***Entamoeba histolytica*** $\rightarrow$ **3** - **Q. African sleeping sickness** $\rightarrow$ Caused by the flagellate ***Trypanosoma brucei gambiense*** (or *T. rhodesiense*), transmitted by tsetse flies $\rightarrow$ **4** - **R. Kala azar (Visceral leishmaniasis)** $\rightarrow$ Caused by the intracellular kinetoplastid ***Leishmania donovani***, transmitted by sandflies $\rightarrow$ **1** - **S. Chagas' disease (American trypanosomiasis)** $\rightarrow$ Caused by ***Trypanosoma cruzi***, transmitted by reduviid triatomine bugs $\rightarrow$ **2** **2. Option Analysis**: - **Option (A) is INCORRECT**: Swaps Kala azar and Chagas disease agents. - **Option (B) is INCORRECT**: Misassigns African sleeping sickness to *T. cruzi*. - **Option (C) [P-3, Q-4, R-1, S-2] is CORRECT**: Perfectly matches all four tropical parasitic protozoan infections. - **Option (D) is INCORRECT**: Misidentifies Amoebiasis pathogen. **3. Final Answer**: - **Correct Choice**: **C**

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