Biomolecules, enzyme kinetics

### **Step-by-Step Solution & Mathematical Derivation (GATE BT 2018 Q.34)** **1. Governing Concept & Definition**: - **Topic**: Stem Cell Biology & Asymmetric Cell Division - In **asymmetric cell division**, a single stem cell divides to generate: - Exactly **one self-renewed stem cell**, and - Exactly **one committed progenitor/differentiated cell**. **2. Detailed Step-by-Step Calculation**: - **Given**: - Starting population $= 1\text{ stem cell}$ - Number of asymmetric cell divisions $= 10$ - In each asymmetric division, the number of stem cells remains constant at 1 because self-renewal produces exactly 1 daughter stem cell while the other daughter cell differentiates. - Therefore, after 10 asymmetric cell divisions, the number of stem cells is strictly 1. **3. Final Answer**: - **Calculated Value**: **1** - **Official GATE Accepted Range**: **1 to 1**