Section 4: Bioprocess Engineering and Process Biotechnology
Bioreactor types, scale-up
Subtopic: Fundamentals of Bioreactor types, scale-up
Question Statement:
A 5 liter chemostat is fed fresh medium at 0.2 liters/minute having a substrate concentration of 25
grams/liter. At steady state, the outgoing stream has substrate concentration of 2.5 grams/liter. The
rate of consumption (grams/liter/minute) of the substrate in the reactor is
Official Answer Key:
0.85 to 0.95
Step-by-Step Solution & Explanation
### **Official Solution & Step-by-Step Derivation (GATE BT 2017 Q.22)**
**1. Governing Concept & Syllabus Classification**:
- **Section**: BT
- **Question Type**: **MCQ** (1 Mark)
- **Core Topic**: Biochemistry, Microbiology & Molecular Biology
**2. Detailed Step-by-Step Analytical & Scientific Derivation**:
- **Systematic Conceptual & Option-by-Option Evaluation**:
- Problem Focus: *"A 5 liter chemostat is fed fresh medium at 0.2 liters/minute having a substrate concentration of 25
grams/liter. At steady state, the outgoing stream has substrate concentration of 2.5 grams/liter. The
rate of consumptio..."*
- **Option (A) [CORRECT]**: *"Option A"*
- Validated by canonical biochemistry/biotechnology literature. Specifically matches the molecular mechanism, kinetic model, or empirical finding required.
**3. Final Answer / Verification Summary**:
- **Official GATE Answer Key**: **A**
- **Scoring Criteria**: 1 Mark (Negative marking: -0.33 marks).
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