Subtopic: Discrete & Continuous Probability Distributions
Question Statement:
While searching a database for similar sequences, E value does NOT depend on the
(A) sequence length (B) number of sequences in the database
(C) scoring system (D) probability from a normal distribution
Options:
(A) sequence length
(B) number of sequences in the database
(C) scoring system
(D) probability from a normal distribution
Official Answer Key:
D
Step-by-Step Solution & Explanation
### **Official Solution & Step-by-Step Derivation (GATE BT 2012 Q.22)**
**1. Governing Concept & Syllabus Classification**:
- **Section**: BT
- **Question Type**: **MCQ** (1 Mark)
- **Core Topic**: Engineering Mathematics
**2. Detailed Step-by-Step Analytical & Scientific Derivation**:
- **Systematic Conceptual & Option-by-Option Evaluation**:
- Problem Focus: *"While searching a database for similar sequences, E value does NOT depend on the..."*
- **Option (D) [CORRECT]**: *"probability from a normal distribution"*
- Validated by canonical biochemistry/biotechnology literature. Specifically matches the molecular mechanism, kinetic model, or empirical finding required.
- **Option (A) [INCORRECT]**: *"sequence length"* does not satisfy the precise boundary conditions or molecular specificity.
- **Option (B) [INCORRECT]**: *"number of sequences in the database"* does not satisfy the precise boundary conditions or molecular specificity.
- **Option (C) [INCORRECT]**: *"scoring system"* does not satisfy the precise boundary conditions or molecular specificity.
**3. Final Answer / Verification Summary**:
- **Official GATE Answer Key**: **D**
- **Scoring Criteria**: 1 Mark (Negative marking: -0.33 marks).
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