GATE BT 2012 • Q10 MCQ • 1 Mark

Section 2: General Biotechnology

Cell structure and signaling

Subtopic: Fundamentals of Cell structure and signaling

Question Statement:

Choose the correct signal transduction pathway.

Options:

  • (A) Hormone → 7 TM receptor → G protein → cAMP → PKA
  • (B) Hormone → G protein → 7 TM receptor → cAMP → PKA
  • (C) Hormone → 7 TM receptor → G protein → PKA → cAMP
  • (D) Hormone → 7 TM receptor → cAMP → G protein → PKA 2012 BIOTECHNOLOGY - BT

Official Answer Key:

A

Step-by-Step Solution & Explanation

### **Official Solution & Step-by-Step Derivation (GATE BT 2012 Q.10)** **1. Governing Concept & Syllabus Classification**: - **Section**: BT - **Question Type**: **MCQ** (1 Mark) - **Core Topic**: Quantitative & Analytical Aptitude **2. Detailed Step-by-Step Analytical & Scientific Derivation**: - **Systematic Conceptual & Option-by-Option Evaluation**: - Problem Focus: *"Choose the correct signal transduction pathway...."* - **Option (A) [CORRECT]**: *"Hormone → 7 TM receptor → G protein → cAMP → PKA"* - Validated by canonical biochemistry/biotechnology literature. Specifically matches the molecular mechanism, kinetic model, or empirical finding required. - **Option (B) [INCORRECT]**: *"Hormone → G protein → 7 TM receptor → cAMP → PKA"* does not satisfy the precise boundary conditions or molecular specificity. - **Option (C) [INCORRECT]**: *"Hormone → 7 TM receptor → G protein → PKA → cAMP"* does not satisfy the precise boundary conditions or molecular specificity. - **Option (D) [INCORRECT]**: *"Hormone → 7 TM receptor → cAMP → G protein → PKA 2012 BIOTECHNOLOGY - BT "* does not satisfy the precise boundary conditions or molecular specificity. **3. Final Answer / Verification Summary**: - **Official GATE Answer Key**: **A** - **Scoring Criteria**: 1 Mark (Negative marking: -0.33 marks).

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